Last time I posted about Jun's progress we had decided to wean of Clonidine. After doing so, I am 100% confident it was the right decision. Jun is much happier and more herself off of it and also much more "even." She is able to relax without being sedated.
After a week of doing behavior logs on just Trazodone and the small amount of Sertaline she gets (so small that it probably isn't doing anything for her), we increased her Sertaline by 50%. I only made it through 6 days of behavior logs on this new dose before I made the decision to reduce it! She was having the same agitation response she had to it the first time we tried to increase it. I emailed Dr. Duxbury the logs and my notes and she agreed that it is time to get Jun off Sertraline altogether and try something else. It's been 3 days off and Jun is still unable to relax (and annoying the hell out of me) but she should be fine by the end of the weekend.
So I will be weaning Jun off Sertraline for the next two weeks and then we will be trying Clomipramine (brand name Clomicalm for animals, commonly known as Anafranil for humans). Interestingly, this is a drug commonly used to treat OCD. I am really interested to see what effect it has, if any, on Jun's sterotypical behaviors, such as tail-chasing and pattern running, and whether it affects her crate barking at all.
Dr. Duxbury is very happy with the results so far of our new behavior mod program, and Jun is doing really well in nosework! At our last class she was a lot more confident and paid less attention to the other people in the room (who have been really great about not watching her while she takes her turns)! I think she is starting to figure out the structure of the class and to understand that while she is working, nobody is going to bother her. At least, I hope that is the case. One of my biggest goals for Jun is building her trust that I won't let anybody touch her if she doesn't want them to. I think/hope nosework class is helping her start to understand that.